Brivaracetam Vs Levetiracetam. Levetiracetam lev and brivaracetam brv are pyrrolidone derivate compounds binding at the presynaptic sv2a receptor site and are thus representative of aeds with a unique mode of action. Briviact brivaracetam can help provide seizure relief if you re already taking 1 or 2 other anti seizure medicines and still having seizures.
Keppra levetiracetam is an anti epileptic drug antoconvulsant often used in conjunction with other drugs to treat types of seizures in people with epilepsy. Lev was extensively investigated in randomized controlled trials and has a very promising efficacy both in focal and generalized epilepsies. Keppra levetiracetam is effective at lowering the frequency of various types of seizures.
However it is still unclear which one has a better efficacy or tolerability for treating patients with rfs.
Along with levetiracetam brivaracetam is also effective in the treatment of myoclonic and generalized tonic clonic seizures. Studies have shown that brv might also be efficacious and well tolerated as adjunctive treatment in patients with rfs. Brivaracetam brv is a highly selective and reversible sv2a ligand with a 15 to 30 fold higher affinity than levetiracetam has in the rat or human brain. Levetiracetam lev and brivaracetam brv are pyrrolidone derivate compounds binding at the presynaptic sv2a receptor site and are thus representative of aeds with a unique mode of action.